Article Type : Research Article
Authors : Lelevich AV, Cai M, Yankovskaya EA, Satsuta PP, Yakimovich EP, Bon EI, and Malenouskaya MYU
Keywords : Blood pressure (BP); Poor nutrition; Circulating blood volume (CBV); Psycho-emotional stress
Arterial hypertension (AH) remains a leading
modifiable risk factor for cardiovascular complications worldwide. Although AH
has traditionally been considered a disease of the elderly, recent
epidemiological studies indicate a trend toward an earlier onset of the
condition, with data demonstrating a steady increase in the prevalence of
elevated blood pressure (BP) among young adults of particular concern is the
growing incidence of AH in university students.
Arterial
hypertension (AH) remains a leading modifiable risk factor for cardiovascular
complications worldwide. Although AH has traditionally been considered a
disease of the elderly, recent epidemiological studies indicate a trend toward
an earlier onset of the condition, with data demonstrating a steady increase in
the prevalence of elevated blood pressure (BP) among young adults [1]. Of
particular concern is the growing incidence of AH in university students. The
period of higher education is characterized by significant psycho-emotional
stress, which, combined with behavioral risk factors, may predispose
individuals to the early development of cardiovascular pathology [2]. Among the
key modifiable risk factors, poor nutrition plays a central role. Current
evidence suggests that an unbalanced diet high in simple carbohydrates directly
affects hemodynamic parameters and contributes to elevated BP [3]. Excessive
intake of fast carbohydrates leads to sharp fluctuations in glucose and insulin
levels. Insulin is known to stimulate the sympathoadrenal system, an effect
observed in both obese and non-obese individuals [4]. Furthermore, insulin
enhances the activity of the sodium-hydrogen exchanger (NHE3) in the renal
tubules, thereby increasing sodium and water reabsorption and raising
circulating blood volume (CBV) [5]. Importantly, this effect may persist even
in the presence of insulin resistance – a phenomenon often described as
"selective insulin resistance" – which further contributes to volume-dependent
hypertension [6]. In contrast to glucose, fructose metabolism in the liver is
accompanied by uric acid production. Hyperuricemia inhibits endothelial nitric
oxide synthase, leading to a deficiency of nitric oxide, a key vasodilator.
This results in endothelial dysfunction and sustained vasospasm [7]. Excessive
dietary salt intake also promotes fluid retention [8] and activates the
sympathoadrenal system [9]. Medical students are particularly vulnerable to
poor dietary habits due to the demanding nature of their training, which often
disrupts regular and balanced nutrition.
The
aim of this study was to assess the prevalence of self-reported episodes of
elevated blood pressure among third-year students at Grodno State Medical
University during the 2025/2026 academic year in relation to their dietary
habits.
The
study included 385 female and 160 male third-year students enrolled at Grodno
State Medical University in the 2025/2026 academic year. All participants
provided voluntary informed consent. Data were collected via a structured
questionnaire addressing the following items: history of elevated BP episodes
(response options: "yes," "no," "don't know");
self-assessed dietary pattern ("balanced," "unbalanced");
and self-reported excessive consumption of salty foods and sweet foods (both
with "yes/no" responses). Students who answered "don't
know" to the question regarding BP episodes were excluded from the
analysis. Data are presented as absolute and relative frequencies (%).
Between-group comparisons were performed using Fisher's exact test. A p-value
of less than 0.05 was considered statistically significant. Statistical
analysis was conducted using StatSoft STATISTICA 10.0 software.
Among female students, episodes of elevated BP were reported more frequently by those with an unbalanced diet (n=179) compared to those with a balanced diet (n=145): 26.82% versus 17.93%, respectively (Table 1).
Table 1: Dietary patterns and self-reported episodes of elevated blood pressure in third-year female students at GRSMU, 2025/2026 academic year, % (n).
|
Dietary Pattern |
n |
No history of
elevated BP |
History of
elevated BP
|
|
Balanced |
145 |
82.07% (119) |
17.93% (26) |
|
Unbalanced |
179 |
73.18% (131) |
26.82% (48) |
Table 2: Excessive salty food intake and self-reported episodes of elevated blood pressure in third-year male students at GRSMU, 2025/2026 academic year, % (n).
|
Excessive Salty
Food Intake |
n |
No history of
elevated BP |
History of
elevated BP
|
|
No |
103 |
76.70% (79) |
23.30% (24) |
|
Yes |
33 |
60.61% (20) |
39.39% (13) |
Table 3: Excessive sweet food intake and self-reported episodes of elevated blood pressure in third-year male students at GRSMU, 2025/2026 academic year, % (n).
|
Excessive sweet food intake |
n |
No history of
elevated BP
|
History of
elevated BP
|
|
No |
86 |
79.07% (68) |
20.93% (18) |
|
Yes |
50 |
62.00% (31) |
38.00% (19) |
Dietary
patterns influence hemodynamic parameters in both female and male third-year
students at GRSMU, as evidenced by a higher incidence of self-reported episodes
of elevated blood pressure among females with unbalanced diets and males who
consume excessive amounts of salty and sweet foods.